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Basically, it makes you feel good

In addition, smokers were not more prone to negative treatment outcomes, although a trend was observed (adjusted odds ratio [OR] 1.24, 95% confidence interval [CI] 0.911.70), and were more likely to be lost to follow-up, but this was also not significant (adjusted hazard ratio [HR] 2.09, 95% CI 0.894.94)

is it any harder to do that by hand though

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At the same time, people ignore educating themselves about other diseases, like oral cancer and many others