Researched applications In the published preclinical and clinical literature the effects of AOD-9604 are documented in the following areas: Obesity , Phase 2b failure (2007), but a complementary mechanism in combination protocols Lipolysis in animal models , robustly demonstrated (Heffernan 2001, Ng 2009) Inhibition of lipogenesis , demonstrated in hepatocytes and adipocytes Osteoarthritis and cartilage regeneration , emerging Phase 1/2 data (mLuna Pharmaceuticals 2018+) Tendinopathy , preclinical models Age-related sarcopenia (cachexia) , exploratory plans Lipodystrophy , preclinical data in animal models Hyperlipidemia , secondary endpoints in Phase 2 trials Science & studies 4.1 Key publications Heffernan M., Summers R.J., Thorburn A., et al
The flora with increased abundance includes Lactobacillus salivarius , Staphylococcus , Corynebacterium , Bacteroides fragilis , Ruminococcus gnavus , Veillonella parvula , Pseudobutyrivibrio , Escherichia/Shigella , and Streptococcus parasanguinis (201, 203, 204)
Life Sci
Longevity will earn credibility the same way cardiology did: risk stratify, measure longitudinally, and stop confusing more numbers with better medicine
Neuropsychopharmacology, 31 (7), 1545-1549
