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In this case, the data show that these nicotine pouch products meet that bar by benefiting adults who use cigarettes and/or smokeless tobacco products and completely switch to these products. Additionally, the FDA found that the applicant showed these nicotine pouch products have the potential to provide a benefit to adults who smoke cigarettes and/or use other smokeless tobacco products that is sufficient to outweigh the risks of the products, including to youth

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The first author (PM) began by reading the transcripts attentively and creating a codebook

This review explores the potential cardiovascular consequences of nicotine pouch use in youth, emphasizing the urgency of evidence-based research to inform clinical guidance, regulatory action, and prevention strategies