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Influence of mutation type on clinical expression of Leber hereditary optic neuropathy

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Agarwal B, Swisher SG , Ajani J, Kelly KK, c F, Komaki RR, Putnam JB, Abu-hamda I, Molke KL, Walsh GL, Correa AM, Ho L, Liao ZX, Lynch PM, Rice DC Smythe WR, Stevens CW, Vaporciyan AA, Yao J, Ja R

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The present study revealed, for the first time, that the liver, tail kidneys, pancreas, and skeletal muscle of HSB had both AGAT and GAMT enzymatic activities (Table 3), with the highest activities of both enzymes in the skeletal muscle