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Th2-induced hyperproduction of the thyroid autoantibodies observed in In Graves disease results in hyperthyroidism

17-hydroxysteroid dehydrogenases Enzymes from the SDR and AKR superfamilies regulate the activity of androgens and estrogens by catalyzing the interconversion of bioactive 17-hydroxy- and inactive keto- containing forms (Fig

PON1 is linked to various conditions including cardiovascular disease (CVD), atherosclerosis, insulin resistance, depression, and T2DM (265267)

Rev Endocr Metab Disord

Second, the role of metabolic reprogramming in ferroptosis highlights how sustained mechanical stress and inflammation reshape lipid, amino acid, iron, and glucose metabolic pathways in OA chondrocytes and synovial cells