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Intestinal bacteria: Thyroid disease and intestinal disease commonly coexist, probably because of disruption of the intestinal barrier, where it is easier for antigens to pass through and react with the immune system or with extra-intestinal tissues to intersect and destroy thyroid cells

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Synthesis of 10-hydroxy- and 9-oxo-2e-decenoic acids from oleic acid

Phase II processes then need to come along and remove that toxic metabolite by conjugating it with another molecule that will facilitate its elimination