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These conditions include cardiovascular disease, diabetes mellitus, cancer, chronic kidney disease, obesity, cataracts, and metabolic syndrome, as well as disorders that impact brain and bone health (1, 2)

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Ethics declarations Ethics approval and consent to participate The study protocol involving human tissues adhered to the Declaration of Helsinki and was approved by the review board of Renmin Hospital of Wuhan University (WDRY2021-KS047)

Development of enzymatic probes of oxidative and nitrosative DNA damage caused by reactive nitrogen species