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Methods A PubMed search was conducted in April 2016 to identify suitable articles published from January 1, 1980 to March 31, 2016

Perfil de actividad documentada Pentadecapeptido gastrointestinal - secuencia de 15 aminoacidos (BPC) Evidencia preclnica predominante en modelos de tejido conectivo, tendon y musculo Revision Sikiric 2018 (Curr Neuropharmacol) - mecanismos documentados en modelo animal Estabilidad superior a peptidos de eje GH a temperatura ambiente Sin RCT humanos de gran escala publicados a la fecha Datos farmacolgicos documentados Mecanismo de accin Mecanismo multifactorial documentado en modelos animales: activacion de via NO-sintetasa, modulacion de VEGF (factor de crecimiento vascular), interaccion con receptores de hormona de crecimiento y proteccion de mucosa GI

Efficacy of berberine in patients with type 2 diabetes

Trolox is more successful than allopurinol to reduce degenerative effects of testicular ischemia/reperfusion injury in rats

KLF10 promotes nonalcoholic steatohepatitis progression through transcriptional activation of zDHHC7