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Neurologic (brain and nerves) Headache Brain fog (memory and concentration problems ) Numbness, pain, or tingling skin Anxiety Behavioural issues, rages Nasal-ocular (nose and eyes) Nose congestion Eye watering and itching Respiratory (lungs and breathing) Sore throat Hoarseness Wheezing Shortness of breath Throat swelling Cardiovascular Chest pain Low blood pressure Fast heart rate Fainting or light-headedness Musculoskeletal Joint and muscle pain Osteoporosis (brittle bones) Loss of bone mass Gastrointestinal Bloating Stomach cramps or pain Reflux Feeling or being sick Diarrhoea Constipation Dumping syndrome Food allergies or intolerance Genital and urinary Genital pain or swelling Pain when urinating Vaginal pain, discharge or itching Bladder urgency or loss of control Dermatologic (skin) Itching with or without a rash Flushing/redness Hives or wheals Swelling General Extreme tiredness Anaphylaxis, which can be life threatening The Histamine Bucket Theory to Explain how MCAS may work You can imagine your body with a histamine bucket thats empty, but exposure to all things in the environment can gradually fill up the bucket to your personal histamine levels

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The researchers had 20 frequent cannabis smokers with respiratory symptoms switch to using a vaporizer for a month

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