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This is explained by their ability to reduce excessive neuronal excitability through hyperpolarization of pyramidal neurons in the prefrontal cortex (5)

doi: 10.1136/pgmj.22.250.205 PMID: 20997404 Biaggioni I (2021): Adrenoceptor Agonists & Sympathomimetic Drugs (Chapter 9)

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This dual-pathway approach to blood vessel formation creates redundancy and amplification, ensuring robust vascular support for healing tissues

T., & Colgan, S