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[DOI] [PubMed] [Google Scholar] 116.Morbidelli L., Donnini S., Ziche M

This study was small and has not been replicated

Concurrently, sustained IFN- feedback further augments local inflammation and T-cell recruitment, potentially through the activation of antigen-presenting cells such as DCs and macrophages [35]

[35] observed that kava extract or a mixture of the 6 six major kavalactones present in the extract inhibited the expression of CYP2C9, CYP2C19, CYP2D6, CYP3A4 in human hepatic microsomes