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if a duct is blocked (by a gallstone, scar-like narrowing/stricture, or a tumor), the drug cant reach its target and adding more bile acids can worsen the backup (jaundice, itching, rising bilirubin/ALP)

While women in developing countries may display lean PCOS phenotypes with severe reproductive dysfunction, women in industrialized countries frequently present with obesity-associated insulin resistance and metabolic syndrome (7)

134 Speak with a physician prior to using a sleep aid to ensure it does not interact with any medications you currently take or affect conditions you have

383 SIRT5-catalyzed demalonylation and inactivation of SDHA block the TCA cycle and induce succinate accumulation, promoting tumorigenesis and drug resistance

ESH 2nd Scientific Workshop on Tumour Environment in Haematological Malignancies, 2017