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Suzuki A, Xiao L, Taketa T, Blum MA, Welsh J, Lin SH, Weston B, Lee JH, Bhutani MS, Rice DC , Mehran RJ, Maru DM, Erasmus JJ, Hofstetter WL, Swisher S, Ajani JA

Docetaxel cleaves GSDME via the ROS/JNK/caspase-3 pathway, and its pyroptotic effect can be enhanced by demethylation of the DFNA5 gene, highlighting the role of epigenetic regulation in chemosensitisation [70]

Zinc IV therapy provides rapid availability of IV zinc compared with oral supplements, making a zinc infusion useful when absorption is limited or faster onset is desired