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doi:10.1016/j.cmet.2015.05.023 Johnson S, Imai SI

Vitamin B12 is a water-soluble nutrient, which means it has an exceptionally high safety profile

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In preclinical studies published in Endocrinology, researchers found that chronic administration of AOD-9604 reduced body weight and body fat in obese mice while increasing beta-3 adrenergic receptor expression to levels comparable with lean mice