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In the hydrogen bond analysis of CME_b, F263 is also a residue in the C1 region, but no additional stable hydrogen bond interactions are observed

Mitochondrial ROS production and oxidative mtDNA damage is increased during reoxygenation in the GPX1 knockout mice, in addition to structural abnormalities in cardiac mitochondria and myocytes, suggesting GPX1 may play an important role in protecting cardiac mitochondria from reoxygenation damage in vivo

The SCX/pS-MIP method is unique with respect to its compatibility with low sample inputs, its programmable selectivity and its low sequence bias in combination with its robustness, speed and simplicity