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This leads to the release and cytoplasmic translocation of p53, which can subsequently activate transcription-independent pro-apoptotic signaling (Clara et al., 2024

Independent lab

Our probe enabled the determination of GSH concentration in the whole cell and three other subcellular compartments, something that would have required four different probes or assays in the past

In addition to the endogenous cellular pathways, recent studies have also investigated the role of the gut microbiome in affecting NAD + levels

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