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The enzyme identified as protein-L-isoaspartate (D-aspartate) O -methyltransferase (encoded by the PCMT1 gene) is required for the repair of deamidated aspartate and asparagine residues in proteins and it utilizes SAM in these reactions

It is a growth hormone secretagogue that works by binding to the ghrelin receptor (GHS-R) in the pituitary gland and hypothalamus ,the same receptor targeted by the hunger hormone ghrelin

Growth hormone fragments have shown potential in stimulating chondrocytes (cartilage-producing cells) and promoting collagen synthesis, which may benefit individuals with osteoarthritis or joint degeneration