Cross-database validation and integrated analyses may help improve signal robustness, particularly when combined with methods such as Bayesian shrinkage or self-controlled case series designs to better account for regional and temporal confounding
Although the anxiety and depression symptom instruments that were used have been validated, they are self-report questionnaires and only evaluated symptom severity, and they do not necessarily have diagnostic value
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however, d-SPE does not optimize pesticide integrity when solvent use is reduced (Zhang et al., 2018a, b)
J Plant Physiol 168:807815 Neill SJ, Desikan R, Clarke A, Hurat RD, Hancock JT (2002) Hydrogen peroxide and nitric oxide as signalling molecules in plants