Sanacora, G., Zarate, C
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Role of redox metabolism in sleep homeostasis It is well-documented that during prolonged sleep deprivation, ROS production is elevated in multiple species and in multiple organs including different regions of the brain (hippocampus, frontal cortex, cerebellum, neocortex), liver, heart, gut, and skeletal muscle (Kempf et al
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Together these results suggested that this antiretroviral therapy compromises the BBB and could be associated with HIV-1 neurological diseases