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Mecobalamin promotes the synthesis of lecithin, the main constituent of medullary sheath lipid, by increasing methionine synthetase activity, thus promoting myelination (phospholipid synthesis)

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IV and short-duration oral trials METAOD001-004 enrolled smaller groups of healthy or obese men with single doses or 1-week dosing across IV (25-400 mcg/kg) and oral (9-54 mg) routes

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