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The drug proved to be so effective that its researchers won the Prize of the Government of the Russian Federation in 2001

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Pathological Consequences of Glutamate Excitotoxicity In general, an excess or prolonged exposure of neurons and glia to high levels of extracellular glutamate during ischemia both lead to a massive Ca 2+ entry into the cells of both gray and white matter (Danysz and Parsons, 2003

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[DOI] [PMC free article] [PubMed] [Google Scholar] 180

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