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Treatment of neonatal female rats with estradiol increases the expression of extrasynaptic 4/ subunit-containing GABA A Rs and improves performance in the Morris water maze during adulthood (209)

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Abstract Adult neurogenesis in the dentate gyrus of the hippocampus is highly regulated by a number of environmental and cell-intrinsic factors to adapt to environmental changes

This does not invalidate the findings, but it is a standard scientific quality consideration that most pages omit