In AD, the brain shows hallmark features of amyloid beta (A) plaque accumulation and neurofibrillary tangles formed by hyperphosphorylated tau protein [2], although prior to diagnosis, a series of neuropathological changes and cognitive decline occur [3]
The intermediates that are formed, such as superoxide (O 2 ) and hydrogen peroxide (H 2 O 2 ), can lead to the production of toxic oxygen radicals that can cause lipid peroxidation and cell injury
Amort T, Rieder D, Wille A, Khokhlova-Cubberley D, Riml C, Trixl L, et al
Every time you eat, breathe, or move, your body uses fuel created from the food you eat to produce energy
38 Clinical course The clinical course of RS is benign and non-progressive, with only mild fluctuations, and is not associated with episodic exacerbations, unlike DJS