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Statin-associated muscle symptoms (SAMS) are the most common toxicity of statins, as shown by manifestations of myalgia, myopathy, myositis with increased creatine kinase (CK), or rhabdomyolysis (Ward et al., 2019), and SAMS risk appears to link with systemic exposure to higher doses of statins (Armitage et al., 2010)

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Cytoprotection against oxidative stress and the regulation of glutathione synthesis

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