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These disturbances, compounded by impaired mitochondrial fatty acid oxidation, ultimately contribute to dyslipidemiacharacterized by elevated serum triglycerides, LDL cholesterol (LDL-C), and total cholesterolwhich accelerates pathological processes such as atherosclerosis and fatty liver disease [119, 120]

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PROLOTHERAPY Derived from the Latin word prolo, meaning to proliferate, regenerate or rebuild, this therapy involves the injection of a mildly irritating substance in to a lesion resulting in localized inflammation with increased blood flow

Moreover, it could have perhaps diminished the activity of urea cycle enzymes, reestablished nitrogen equilibrium, and maybe adjusted or enhanced the nitrogen levels in organs

J Mol Cancer Ther