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Storage Store vials at 20 C 25 C (68 F 77 F), protected from excessive heat and direct light

When treating vitamin B12 deficiency, Hydroxocobalamin 20 mg/ml Injection Solution is usually administered as a single intramuscular or intravenous injection, followed by monthly injections for up to 6 months

Given that the mitochondrial membrane potential typically ranges from 140 to 180 mV, the TPP cation is able to accumulate several hundred-fold within the mitochondrial matrix, presenting a highly efficient targeting ability

Further, circadian clocks disruption might also be an important factor to IR development via various factors including clock gene mutations, disturbed sleep cycles, shift work and jet lag

Absence of head-to-head human comparison There is no published human study that directly compares injectable GHK-Cu against topical GHK-Cu for any skin endpoint