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For instance, honokiol, a biphenolic compound from Magnolia officinalis , has been shown to significantly reduce ergosterol levels in Candida albicans , thereby compromising membrane integrity and exerting direct antifungal effects (Sun LM

Wessel MJ, Zimerman M, Timmermann JE, Heise KF, Gerloff C, Hummel FC

Mechanisms of cognitive dysfunction in CKD

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Research suggests it may upregulate collagen expression and growth factor signaling in cell and animal models, though translation to clinical efficacy in humans remains preliminary and requires additional rigorous studies