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In EAE mice, adoptive transfer of itaconate-treated, Th17-polarized T cells significantly ameliorated disease severity (173), highlighting the potential of targeting metabolic pathways to modulate the Th17/Treg balance in autoimmune neuroinflammation

Association of Markers of Inflammation, the Kynurenine Pathway and B Vitamins with Age and Mortality, and a Signature of Inflammaging

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In another in vivo study, a reduction in levels of testosterone and an increase in levels of LH and FSH were seen after NAC supplementation among adult male Wistar rats (Reference Moghadam, Shariati and Naeimi16)

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