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[165] The extensive hepatic metabolism of melatonin means that patients with liver disease may experience prolonged drug effects and increased risk of accumulation

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Notably, the beneficial roles of taurine in the context of diabetes have been widely studied in recent years (Ito et al., 2012)

doi: 10.1007/s00296-011-2326-8 274 DerambureCDzangue-TchoupouGDAgostinoMALequerrTVittecoqO

Basal ganglia-thalamocortical circuits: parallel substrates for motor, oculomotor, prefrontal and limbic functions