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This protection reduces unnecessary apoptosis a form of programmed cell death that, when excessive, can deplete healthy cells and weaken tissues.16 TUDCA clearly alters bile chemistry under cholestatic stress, but most evidence for its cellular effects still comes from cell and animal studies

The previously formed carbanion performs a nucleophilic attack on the carbonyl carbon of glyceraldehyde 3-phosphate

doi: 10.1038/ncpendmet0621 116 SedelnikovaOARedonCEDickeyJSNakamuraAJGeorgakilasAGBonnerWM

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