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The mechanism behind this laboratory artifact remains unclear, but it means some patients may receive unnecessary b12 supplementation based on misleading test results
They measure how much B12 functions in the cells
Notably, the 1,4-dihydropyridine ring oxidized analogue (KL7) completely lost the adjuvant activity, presumably due to altered electronic structure, reduced conformational flexibility, or lost hydrogen bonding capacity (Extended Data Fig
Youre going about your day when all of a sudden, your heart starts beating so fast it feels like its going to burst out of your chest
