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Pro-oxidant substances can act through two main pathways: Increasing the formation of ROS: Certain substances can increase the production of ROS, which, in turn, can act as pro-oxidants themselves

Because many extensive reviews have been published on each [109,110,111,112,113,114,115,116], we will focus our discussion herein on recent discoveries in this topic

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Accumulation of these heavy metals and toxic compounds can lead to health issues that are often vague and hard to evaluate