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Ageing Res Rev 60:101046 Van Acker ZP, Bretou M, Annaert W (2019) Endo-lysosomal dysregulations and late-onset Alzheimers disease: impact of genetic risk factors

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Studies have shown that hypoxic conditions within the TME reduce STAT3 activity in myeloid cells, a process linked to increased CD45 phosphatase activity