[300-303] But it is a type of chelator that does not redistribute to other tissues, which is a big risk in many chelation therapies.[304-308] Natural compounds such as N-acetyl L-cysteine, alpha lipoic acid and glutathione all contribute to chelation and excretion of metals in the human body with much less risk of displacement into other tissues, such as the brain, than synthetic chelating agents.[309,310] These compounds also serve as antioxidants in the tissue to protect the tissue from damage caused by interaction with heavy metals.[311-313] Oxidative stress may be considered as one of the prime contributing mechanisms in metal toxicity and thus provide a strong rationale for including antioxidants during chelation therapy.[314] Antioxidant supplementation with chelating agents has been found beneficial in increasing metal mobilization and providing improved recovery from problems associated with chelation therapy [315-317]
Effects of chenodeoxycholate and a bile acid sequestrant, colesevelam, on intestinal transit and bowel function
Reactive nitrogen species generated by heme proteins: Mechanism of formation and targets
Find glycine in animal products like meat, low-temperature treated whey protein, bone broth, or at lower levels in veggie proteins like nuts and beans
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