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Structural & Functional Notes GHK-Cu is a naturally occurring tripeptide complex capable of binding copper ions within biological signaling environments

10.3389/fimmu.2019.02655 448 ValeriF.Dos Santos GuilhermeM.HeF.StoyeN

After deproteination with TCA15, both samples were analyzed by HPLC

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This change is associated with reduced commensal Clostridiales and increased oral Lactobacillales, and the transcription level of CYP8B1, a key enzyme in bile acid synthesis, is reduced, indicating that HCV infection alters bile acid metabolism through the gut-microbiota-liver axis