BPC-157 (Body Protection Compound, 15-residue pentadecapeptide) and TB-500 (synthetic fragment of thymosin beta-4) are extensively co-investigated in soft-tissue, angiogenesis and cell-migration research
Neither interferes with the other's molecular target, receptor binding, or downstream signaling
The H-ESI source was operated in positive mode at spray voltage 3,500 or negative mode at spray voltage 2,500 with the following parameters: sheath gas 35 a.u., aux gas 7 a.u., sweep gas 0 a.u., ion transfer tube temperature 320 C, vaporizer temperature 275 C, mass range 70 to 1,000 m/z , full scan MS1 mass resolution of 120,000 FWHM, RF lens at 70% and standard AGC
PMCID: PMC7569385
One suggested mechanism is that air pollutants can disrupt iron homeostasis by chelating or displacing iron from pivotal sites in the cell, which results in absolute or functional cell ID, which could contribute to increased risk of IDA with long-term exposure to air pollutants (appendix p