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Low glutathione levels increase the cellular risk for free radical damage, and are found in a wide range of health conditions associated with oxidative stress and inflammation

In a model of primary sclerosing cholangitis (PSC), MSC-EVs reduced liver fibrosis, dampened immune cell infiltration, and suppressed NF-B activation, highlighting their capacity to modulate inflammation and fibrotic pathways [190]

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Some researchers also report increased water retention