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Furthermore, mortality may be measured by the percent of people that pass away over a period of time, since being diagnosed with liver cirrhosis [10]

Glutathione (GSH) is an important antioxidant that protects against ferroptosis and it can be synthesized via cystine uptake mediated by cystine/glutamate antiporter xCT (Lim et al., 2019)

It also normalized levels of neurotransmitters and hormones in various stress conditions (leading some to propose it has a balancing effect on the brain-gut axis )

Enhancing the specificity of ferroptosis activators and regulating their dosage to minimize adverse effects on healthy tissues are anticipated to represent novel oncological therapeutic strategies