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Among the upregulated genes are those encoding DNA repair enzymes (BRCA1, ATM), extracellular matrix proteins (COL1A1, COL3A1, ELN) and antioxidant enzymes (SOD1, SOD2, GPX)

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The skin is highly vulnerable to inflammatory and immune-mediated disorders

Symptoms of Poor Sleep: Daytime fatigue, irritability, poor concentration, and reliance on caffeine to get through the day

Predictors of improvement and progression of diabetic polyneuropathy following treatment with alpha-lipoic acid for 4 years in the NATHAN 1 trial