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This is a significant advantage over full-length growth hormone, which worsens insulin resistance

10.1126/science.179.4068.77 14 BrownM

While both contain the GHK-Cu peptide, cosmetic grades might incorporate additional carriers, stabilizers, or inactive ingredients that are not disclosed or relevant for research purposes

However, as with any biological therapy, the theoretical possibility of individual hypersensitivity cannot be entirely eliminated, and appropriate monitoring remains prudent

Whether that gain holds up against retatrutide's already-stronger backbone is the open empirical question additive effects often diminish as the base compound's efficacy increases