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doi: 10.3389/fnut.2020.00101 [DOI] [PMC free article] [PubMed] [Google Scholar] 33.Rodrguez-Negrete EV, Morales-Gonzlez , Madrigal-Santilln EO, Snchez-Reyes K, lvarez-Gonzlez I, Madrigal-Bujaidar E, et al

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However, the long-term safety of nanomaterials requires further investigation, particularly regarding the metabolic pathways of their degradation products, their effects on the immune system, and potential accumulation-related risks