doi: 10.1371/journal.pntd.0001569 38 Duvaux-MiretOStefanotGBSmithsEMDissousCCapronA
A small-molecule inhibitor suppresses the tumor-associated mitochondrial NAD(P)+-dependent malic enzyme (ME2) and induces cellular senescence
Furthermore, Hu et al (42) discovered that the downregulation of the GPX3 gene resulted in a decrease in the wound healing capacity and transmembrane migration rate of OC and colorectal cancer cells
A novel transgenic mouse model of growth plate dysplasia reveals that decreased chondrocyte proliferation due to chronic ER stress is a key factor in reduced bone growth
A recent meta-analysis of 16 trials investigated 12 Chinese herbal formulas, three Chinese patent medicines, and one single herbal medicine highlighting both immunological and symptomatic outcomes in HT patients ( Astragalus membranaceus (Fisch.) Bge., Codonopsis pilosula (Franch.) Nannf., Angelica archangelica L., Atractylodes macrocephala Koidz., Ligusticum chuanxiong Hort., Paeonia lactiflora Pall., Curcuma longa L., Poriacocos (Schw.) Wolf., Citrus aurantium L., Pinellia ternata (Thunb.) Makino, Fritillaria thunbergii Miq.) 10 gr twice/day resulted in the best reduction of both TPOAb and TGAb compared to placebo, but changes in clinical symptoms were not evaluated
