However, VEGF pathway activation in the context of normal tissue repair differs substantially from VEGF activity in established tumors
- Not FDA-approved for human use commonly available through research and compounding pharmacies
Cognitive dysfunction was assessed via novel object recognition testing, where ketamine 3 mg/kg impaired rats ability to distinguish new objects from familiar ones
Stereological brain sampling of the areas of interest was performed and brain were serially cut on a cryostat (Leica Biosystems, Germany, cat# CM3050S), mounted on Superfrost Plus slides (Thermo Fisher Scientific, Reinach, Switzerland), and cryoprotected in 50% of PB, 30% of ethylene glycol, 20% of glycerol, and subsequently stored at 20 C
The Journal of cell biology 2013;203, 929942, doi: Kirkland, J