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The review proposes BPC-157 may have its own presence in synaptic vesicles, maintaining vesicle integrity and function while competing for receptor sites and substituting for neurotransmitters when neurons are damaged or depleted

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These drugs exert their effects by inhibiting the thiazide-sensitive Na + /Cl cotransporter identified as NCC (also identified as NCCT: encoded by the SLC12A3 gene)