Signs in infants and young children (often appearing around 4-6 months): Irritability and sleep disturbances Developmental delays or regression Poor muscle tone and coordination problems Speech difficulties White matter abnormalities on brain imaging In adults: Movement disorders Balance and coordination problems Cognitive decline and memory loss Mood changes The symptoms can range from mild behavioral changes to severe, progressive neurological deterioration
Effect of supplement with lactic-acid producing bacteria on fatigue and physical activity in patients with chronic fatigue syndrome
However, in plant kingdom, only an amino acid and a protein, namely the glutamate (Glu) and the recently discovered Riccas factor -THIOGLUCOSIDE GLUCOHYDROLASE (TGG) are so far defined as wound signals that depend on glutamate receptor-like (GLR) protein, the homologous protein of mammalian ionotropic Glu receptors (iGluRs), to activate systemic plant defense response 6,7,11
Nat Biotechnol 26:13671372 Cui XS, Li XY, Kim NH (2007) Cdc42 is implicated in polarity during meiotic resumption and blastocyst formation in the mouse
Local, state, and federal policymakers should follow this example targeting the actual high-risk substances, not banning safe, widely used kratom that is helping people every day
