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Elevated levels of endogenous oxidative stress may also be related to disease burden, medication regimen, and duration of treatment, age, and excessive physical and emotional stress associated with comorbid medical conditions (34)

1997.View Abstract [2] Gul M, Kutay FZ, Temocin S, Hanninen O

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Compared to use of a placebo (84 patients) in this trial, use of -tocopherol (85 patients) significantly slowed progression of Alzheimer's dementia, evidenced by significant improvements on the Blessed Dementia Scale and time to institutionalization (122)