2018 pilot study liposomal glutathione 12 healthy older adults in Skin Aging and Tissue Regeneration: A Systematic Review of Molecular Mechanisms, Redox Modulation, and Biomedical Implications How to Increase Cellular Glutathione

Exposure to outdoor elements, primarily ultraviolet (UV) irradiation and oxidative stress is the main cause for photoaging

Single-cell transcriptomic analysis reveals gut microbiota-immunotherapy synergy through modulating tumor microenvironment

For example, intranasal administration of edaravone PLGA nanoparticles showed improved brain stability and bioavailability and reduced H 2 O 2 -induced oxidative stress toxicity in mouse microglial cell line BV-2 (Lu et al., 2023)

Although there is no corresponding research report at present, this method undoubtedly provides a new idea and strategy for the treatment of breast cancer

Considering the many limitations of intravenous glutathione, it is prudent that dermatologists refrain from administering such injections for skin lightening until further trials and high quality studies establish a favourable benefit versus risk ratio that justify its use [Box 7]