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Targeting HSP90-epichaperome in TP53 mutant AML

These primed SCs convert most glucose to lactate, facilitating the recycling of NAD from the cytosol and ensuring their utilization in other cellular synthesis pathways

An experimental model using prenatal treatment of bromodeoxyuridine-rats showed YKS had favorable effects on cerebellar serotonin metabolism, enhancing cognitive ability and reducing locomotor agitation, making it a suitable model for studying ADHD and ASD [161]

These include subgroups with hyperactive mitochondrial respiration, partial disfunction, or classical mitochondrial disease patterns, each potentially associated with different clinical features such as neurodevelopmental regression or immune malfunction (Frye et al., 2024)

Recovery typically 1 to 3 weeks with conventional treatment