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In addition, Cox2, the marker of lipid peroxidation during ferroptosis, was significantly reduced after DMF treatment

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Without adequate CoQ10, this conversion process slows down.* CoQ10 is most highly concentrated in tissues with the greatest energy demands the heart, liver, and kidneys

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Physiologically, this lowering of GSH led to increased LDH release ( P = 0.031), consistent with redox activation of ferroptosis and cell death (Figure 4C and refs