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In parallel, developing multidisciplinary molecular biological techniques (omics) try to investigate the background of these diseases using microbial, immunological, environmental, and genetic approaches ( Immunological examinations have found that the mucosal immune system has a crucial role in the regulation of gut microbiotic homeostasis through optimizing normal and dysbiotic microbiome balance ( Bacteroides spp

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The de novo synthesis employs 5-phosphoribosyl-1-pyrophosphate, aspartate, glycine, glutamine, HCO 3 and 10-formyltetrahydrofolateas for building blocks, which could be found in all plants, such as tea-leaves